L r eol dating
however, the causative agent for the disease was only discovered in 1901 as a concurrent finding by William Boog Leishman and Charles Donovan. Some of these names suggest links to negative cultural beliefs or mythology, which still feed into the social stigmatization of leishmaniasis today. The four genera Leptomonas, Crithidia, Leishmania, and Endotrypanum form the terminal branches, suggesting a relatively recent origin. Trypanosoma cruzi groups with trypanosomes from bats, South American mammals, and kangaroos suggest an origin in the Southern Hemisphere. The remaining clades in this tree are Blastocrithidia, Herpetomonas, and Phytomonas. Due to its broad and persistent prevalence throughout antiquity as a mysterious disease of diverse symptomatic outcomes, leishmaniasis has been dubbed with various names ranging from "white leprosy" to "black fever".
Lipophosphoglycan has a role in resisting the complement system, inhibiting the oxidative burst response, inducing an inflammation response and preventing natural killer T cells recognising that the macrophage is infected with the Leishmania parasite.
Leishmania species are unicellular eukaryotes having a well-defined nucleus and other cell organelles including kinetoplasts and flagella.
About 2 million new cases occur each year, and 21 species are known to cause disease in humans.
(V.) braziliensis has been proposed as the type species for this subgenus.
The species in the Viannia subgenus develop in the hind gut: L.